Dr. Solomon Ali
Associate Professor Medical Microbiology at St. Paul’s Hospital Millennium Medical College (SPHMMC)
Dr. Solomon Ali is working as an Associate Professor of Medical Microbiology at St. Paul's Hospital Millennium Medical College in Addis Ababa, Ethiopia. He has published 48 scientific research articles on reputed journals including Nature Communications, Lancet Global Health, Frontiers Microbiology, Genes, and antimicrobial resistance and infection control focusing on MTB, multi-drug-resistant bacteria, and SARS-CoV-2.
His MTB research is centered around understanding the molecular epidemiology mainly the origin, global distribution, population structure and transmission dynamics of M. tuberculosis complex, diagnosis and treatment challenges of TB diseases in Ethiopia. He has explored the prevalence of MTB in different high risk populations, the effectiveness of diagnostic tools, and the emergence of drug-resistant MTB strains. His studies often emphasize the need for improved public health interventions to halt transmission, and laboratory capacity building for early detection and management of TB in resource-limited settings.
He has investigated the prevalence and mechanisms of antibiotic resistance in clinical settings highlighting the public health threat posed by MDR pathogens. He has explored the gene signatures underlying antibiotic resistance, focusing on the role of extended-spectrum beta-lactamases (ESBLs) and carbapenemase genes among selected Gram negative bacteria. His findings provided insights into how these bacteria acquire and disseminate resistance, which is crucial for developing targeted interventions particularly the need for robust antibiotic stewardship programs.
Solomon has significantly contributed to the understanding of COVID-19 in Ethiopia, focusing on the epidemiology, clinical features, and public health response to the pandemic. His research includes studies on the spread of the virus, risk factors for severe disease, and the impact of the pandemic on the healthcare system. He has examined the effectiveness of public health measures and predicted natural infection and/ or vaccine induced immunity and cross immunity at different waves of SARS-CoV-2 variant transmission in the Ethiopian context.